Lebitso le akaretsang: | Desmopressin Acetate |
Nomoro ea Cas: | 16789-98-3 |
Foromo ea molek'hule: | Setšoantšo sa C48H68N14O14S2 |
Boima ba molek'hule: | 1129.28 g/mol |
Tatelano: | Mpr-Tyr-Phe-Gln-Asn-Cys-Pro-D-Arg-Gly-NH2 |
Ponahalo: | Phofo e tšoeu e hlephileng |
Kopo: | Desmopressin acetate ke mofuta oa maiketsetso oa hormone ea antidiuretic vasopressin. Haholo-holo e sebelisoa ho phekola maemo a bakang ho ntša metsi ka mokhoa o feteletseng le lenyora le feteletseng, joalo ka lefu la tsoekere insipidus le ho ntša metsi liphateng. Desmopressin acetate e sebetsa ka ho eketsa bongata ba metsi a liphio, ka hona e fokotsa bongata ba moroto o hlahisoang. E boetse e thusa ho laola ho leka-lekana ha mokelikeli oa 'mele, ho ntlafatsa metsi le ho fokotsa lenyora le feteletseng. Meriana ena e fumaneha ka mefuta e mengata, ho kenyelletsa matlapa, nasal spray le ente. Tekanyo le tsamaiso li ipapisitse le boemo bo itseng bo alafshoang le karabelo ea motho ho moriana. Desmopressin acetate hangata e mamelloa hantle, 'me ho na le litla-morao tse fokolang tse tlalehiloeng. Leha ho le joalo, ho lokela ho hlokomeloa batho ba nang le maemo a itseng a bophelo, a kang mathata a liphio kapa khatello e phahameng ea mali. Ha u nka desmopressin acetate, ho bohlokoa ho latela litekanyetso tse behiloeng le litaelo tse fanoeng ke setsebi sa tlhokomelo ea bophelo. Ho ka 'na ha hlokahala hore u behe leihlo kamehla ho netefatsa hore moriana o sebetsa hantle ebile o bolokehile. Qetellong, desmopressin acetate ke moemeli oa bohlokoa ho phekola matšoao a polyuria le lenyora. E thusa ho laola tekano ea mokelikeli le ho fokotsa matšoao a amanang le maemo ana. Leha ho le joalo, tšebeliso e lokela ho ba tlas'a tataiso ea setsebi sa tlhokomelo ea bophelo ho etsa bonnete ba hore litekanyetso le tlhokomelo e nepahetseng. |
Sephutheloana: | aluminium foil bag kapa aluminium TIN kapa ho latela litlhoko tsa moreki |
1 | Morekisi oa litsebi oa li-API tsa peptide ho tsoa Chaena. |
2 | Mehala ea tlhahiso ea 16 e nang le matla a lekaneng a tlhahiso a maholo ka theko ea tlhōlisano |
3 | GMP le DMF li fumaneha ka litokomane tse tšepahalang haholo. |
A: E, re ka paka e le tlhoko ea hau.
A: LC sight le TT esale pele nako ea tefo e khethiloeng.
K: E, ka kopo fana ka litlhaloso tsa hau tsa boleng, re tla hlahloba R&D ea rona mme re leke ho tsamaisana le litlhaloso tsa hau tsa boleng.