GMP grade Degarelix acetate API e nang le faele ea DMF
| Lebitso le akaretsang: | Degarelix acetate |
| Nomoro ea Cas: | 214766-78-6 |
| Foromo ea molek'hule: | C82H103ClN18O16 |
| Boima ba molek'hule: | 1632.28 g/mol |
| Tatelano: | Ac-D-2-Nal-D-4-Cpa-D-3-Pal-Ser-4-amino-Phe(L-hydroorotyl)-4-ureido- D-Phe-Leu-Lys(isopropyl)-Pro- D-Ala-NH2 letsoai la acetate |
| Ponahalo: | Phofo e tšoeu |
| Kopo: | Degarelix acetate ke setlhare se sebelisoang ho alafa mofetše o tsoetseng pele oa tšoelesa ea senya.Ke ea sehlopha sa lithethefatsi tse bitsoang gonadotropin-releasing hormone (GnRH) antagonists.Ho fapana le li-agonists tsa GnRH, tse qalang ho susumetsa tlhahiso ea testosterone ebe li theola testosterone, degarelix acetate e thibela ka ho toba ketso ea GnRH, kahoo e fokotsa maemo a testosterone 'meleng.Ka ho theola maemo a testosterone, degarelix acetate e thusa ho liehisa kholo ea lisele tsa mofetše oa senya.E kenngoa ka tlas'a letlalo hang ka khoeli.Degarelix acetate e bonts'itsoe e sebetsa ho fokotsa maemo a testosterone ka potlako le ho a boloka a le ka har'a mefuta e hlokahalang bakeng sa kalafo ea mofetše oa senya.Degarelix acetate ke khetho ea bohlokoa ea kalafo bakeng sa banna ba nang le mofetše o tsoetseng pele oa tšoelesa ea senya ba sa khoneng kapa ba sa batleng ho etsoa opereishene kapa ho noa meriana e theolelang maemo a testosterone.Ka kakaretso e mamelloa hantle, 'me litla-morao tse tloaelehileng li kenyelletsa karabelo ea sebaka sa ente, ho fufuleloa, likhahla tse chesang, le ho fokotseha ha libido.Ka kakaretso, degarelix acetate ke khetho e sebetsang le e netefalitsoeng ea kalafo bakeng sa mofetše o tsoetseng pele oa tšoelesa ea senya, e thusang ho laola lefu lena le ho ntlafatsa boleng ba bophelo ba mokuli. |
| Sephutheloana: | aluminium foil bag kapa aluminium TIN kapa ho latela litlhoko tsa moreki |
| 1 | Morekisi oa litsebi oa li-API tsa peptide ho tsoa Chaena. |
| 2 | Mehala ea tlhahiso ea 16 e nang le matla a lekaneng a tlhahiso a maholo ka theko ea tlhōlisano |
| 3 | GMP le DMF li fumaneha ka litokomane tse tšepahalang haholo. |
A: E, re ka paka e le tlhoko ea hau.
A: LC sight le TT esale pele nako ea tefo e khethiloeng.
K: E, ka kopo fana ka litlhaloso tsa hau tsa boleng, re tla hlahloba R&D ea rona mme re leke ho tsamaisana le litlhaloso tsa hau tsa boleng.
Ngola molaetsa wa hao mona mme o re romele wona
